⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270059 | 0.73 | — | — | |
| SCHEMBL270155 | 0.71 | — | — | |
| SCHEMBL11187840 | 0.71 | — | — | |
| SCHEMBL1410618 | 0.69 | — | — | |
| SCHEMBL15333026 | 0.69 | — | — | |
| SCHEMBL276980 | 0.69 | — | — | |
| SCHEMBL1267481 | 0.69 | — | — | |
| SCHEMBL56766 | 0.69 | — | — | |
| SCHEMBL1266944 | 0.69 | — | — | |
| SCHEMBL9021368 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164997-A | Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118164998-A | Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| US-10793884-B2 | Methods and materials for making simvastatin and related compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-10-06 | — | — | US | claimed |
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | claimed |
| EP-3430022-B1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDITE FOR INCORPORATION INTO A NUCLEIC ACID SEQUENCE | SOMALOGIC INC (US) | 2020-03-11 | — | — | EP | claimed |
| CN-105585565-B | - 4- thiazole the pyridine derivative of anilino- containing 2- and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2019-10-01 | — | — | CN | claimed |
| CN-109369587-A | A kind of production technology of high-purity high-yield Envidor | 新沂市永诚化工有限公司 | 2019-02-22 | — | — | CN | claimed |
| US-20180355391-A1 | METHODS AND MATERIALS FOR MAKING SIMVASTATIN AND RELATED COMPOUNDS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-12-13 | — | — | US | claimed |
| US-4997755-A | Enzyme inhibitors, anticholesterol, biosynthesis | MERCK & CO., INC. (US) | 1991-03-05 | — | — | US | claimed |
| EP-0404581-A2 | Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs | MERCK & CO. INC. (US) | 1990-12-27 | — | — | EP | claimed |
| US-4965200-A | BIOSYNTHESIS, AEROBIC PROCESS; ANTICHOLESTEROL | MERCK & CO., INC. (US) | 1990-10-23 | — | — | US | claimed |
| EP-0391188-A1 | Fungicide agents based on partly known nitro substituted benzothiazolones, new nitro substituted benzothiazolones and process for their preparation | BAYER AG (DE) | 1990-10-10 | — | — | EP | claimed |
| EP-0381478-A1 | Process for the preparation of 6-alpha-hydroxymethyl lovastatin derivatives | MERCK & CO. INC. (US) | 1990-08-08 | — | — | EP | claimed |
| EP-0337548-A2 | HMG-COA reductase inhibitors produced by nocardia SP. (MA6455)(ATCC 53695) | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0142146-B1 | OXO-ANALOGS OF MEVINOLIN-LIKE ANTIHYPERCHOLESTEROLEMIC AGENTS | MERCK & CO. INC. (US) | 1988-08-31 | — | — | EP | claimed |
| EP-0173510-A2 | Tripeptide derivatives for use as anti-hypertensive agents | AJINOMOTO CO., INC. (JP) | 1986-03-05 | — | — | EP | claimed |
| EP-0142146-A2 | Oxo-analogs of mevinolin-like antihypercholesterolemic agents | MERCK & CO. INC. (US) | 1985-05-22 | — | — | EP | claimed |
| EP-0137444-A2 | Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-Decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one | MERCK & CO. INC. (US) | 1985-04-17 | — | — | EP | claimed |