SCHEMBL27022485

SCHEMBL27022485

CC(=O)Nc1ncc(CN2CCN(CC(O)Nc3nc4c(Cl)cccc4s3)CC2)s1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 18/20 0.53
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27008691 0.86 OGA (0.66) OGAKMT2A
SCHEMBL29057509 0.73 OGA (0.48) OGAMEN1KMT2A
SCHEMBL30754208 0.72 DYRK1A (0.71) MEN1KMT2A
SCHEMBL30620440 0.72 OGA (0.72) OGA
SCHEMBL26349079 0.72 OGA (0.72) OGA
SCHEMBL20281964 0.70 SMN1; SMN2 (0.74) OGA
SCHEMBL27022312 0.69 OGA (1.00) OGA
SCHEMBL16112796 0.69 OGA (0.71) OGAKMT2A
SCHEMBL16113448 0.69 SMN1; SMN2 (0.76) OGA
SCHEMBL27008520 0.69 OGA (0.77) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE OGA 1/4885MEN1 2839/4885KMT2A 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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