Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502658 | 0.90 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL22502497 | 0.90 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL22502547 | 0.90 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL26206267 | 0.90 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL22526961 | 0.90 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL22502556 | 0.90 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL22526744 | 0.90 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL22526964 | 0.90 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL23540794 | 0.87 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL22502682 | 0.85 | CRBN (0.72) | DDB1CRBNHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | STAT4, STAT1, STAT3 | DDB1 3993/4885CRBN 171/4885POLB 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.