Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
| ▸ | FEN1 | P39748 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27027373 | 0.97 | CYP3A4 (0.38) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL27027368 | 0.95 | CYP3A4 (0.32) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL27027382 | 0.85 | CYP3A4 (0.39) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL24300895 | 0.85 | CYP3A4 (0.37) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL24300914 | 0.84 | CYP3A4 (0.35) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL24300898 | 0.84 | CYP3A4 (0.37) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL24300896 | 0.83 | ESR2 (0.38) | ALOX5APFEN1CYP3A4CYP2C9APP | |
| SCHEMBL27027377 | 0.82 | CHKA (0.31) | ALOX5APFEN1GRIN2B | |
| SCHEMBL27027384 | 0.82 | CYP3A4 (0.41) | CYP3A4CYP2C9APPESR1ESR2 | |
| SCHEMBL24300894 | 0.81 | CYP3A4 (0.36) | ALOX5APFEN1CYP3A4CYP2C9APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133361-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024133363-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-20240067879-A1 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240067879-A1 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| EP-4306615-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-01-17 | — | — | EP | disclosed |