SCHEMBL27028331

SCHEMBL27028331

CCCCCCCCCCCCCCCCCCCC[Si](CCCCCCCCCCCCCCCCCCCC)(CCCCCCCCCCCCCCCCCCCC)OC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 3/20 0.43
EPHX1 P07099 1/20 0.38
DNM1 Q05193 6/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27028330 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL27028334 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL610669 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL19356773 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL19356606 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL15847432 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL19356691 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL612829 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL610798 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1
SCHEMBL27245246 1.00 TSHR (0.44) TSHRTHRBLMNAEPHX1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199913-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-20 US disclosed
EP-4309006-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE Tokyo Ohka Kogyo Co., Ltd. (JP) 2024-01-24 EP disclosed
WO-2022213043-A1 METHOD FOR SUPPRESSING COLLAPSE OF THREE-DIMENSIONAL STRUCTURE TOKYO OHKA KOGYO CO., LTD. (JP) 2022-10-06 WO disclosed
CN-109071366-B Surface applied corrosion inhibitor 建筑研究和技术有限公司 2022-05-10 CN disclosed