SCHEMBL270298

SCHEMBL270298

[CH2]CC(O)C(C)(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6618293 0.78
SCHEMBL3167201 0.77
SCHEMBL8150185 0.75
SCHEMBL3162713 0.73 TSHR (0.31)
SCHEMBL283398 0.71
SCHEMBL16621830 0.71
SCHEMBL2669556 0.71
SCHEMBL6543364 0.71
SCHEMBL4752268 0.71
SCHEMBL10743716 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1026155-A1 VITAMIN D DERIVATIVES AND PROCESS FOR PRODUCING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-08-09 EP claimed
US-6072062-A Synthesis of C18 -modified vitamin D compounds and compounds resulting therefrom DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 2000-06-06 US claimed
US-5824811-A 22-Thiavitamin D3 derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1998-10-20 US claimed
US-5637742-A Vitamin D compound, method of preparing this compound and intermediate therefor DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1997-06-10 US claimed
EP-0521550-B1 Vitamin D compound, method of preparing this compound and intermediate therefor DUPHAR INT RES (NL) 1996-09-18 EP claimed
EP-0521550-A2 Vitamin D compound, method of preparing this compound and intermediate therefor DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1993-01-07 EP claimed
CN-107216864-B The preparation and its application of sulfobetaines of the one kind containing double long-chain alkoxy bases 江南大学 2019-10-25 CN disclosed
CN-107216864-A One class contains the preparation and its application of the sulfobetaines of double long-chain alkoxy bases 江南大学 2017-09-29 CN disclosed
US-9567355-B2 Hepatitis C inhibitors and uses thereof ABBVIE INC. (US) 2017-02-14 US disclosed
US-20160355530-A1 HEPATITIS C INHIBITORS AND USES THEREOF ABBVIE INC. 2016-12-08 US disclosed
US-20160338991-A1 NOVEL COMPOUND OBTAINED FROM GAMBOGE RESIN, AND MEDICAL USES OF THE SAME TAIWAN SUNPAN BIOTECHNOLOGY DEVELOPMENT CO., LTD 2016-11-24 US disclosed
US-9498463-B2 Compound obtained from gamboge resin, and medical uses of the same TAIWAN SUNPAN BIOTECHNOLOGY DEVELOPMENT CO., LTD. (TW) 2016-11-22 US disclosed
US-9453007-B2 Hepatitis C inhibitors and uses thereof ABBVIE INC. (US) 2016-09-27 US disclosed
US-5977092-A Drug for curing/ameliorating concomitant syndrome of tumor CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1999-11-02 US disclosed
EP-0947504-A1 16-ENE-VITAMIN D DERIVATIVES Chugai Seiyaku Kabushiki Kaisha (JP) 1999-10-06 EP disclosed
US-5824811-A 22-Thiavitamin D3 derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1998-10-20 US disclosed
EP-0870503-A1 MALIGNANT TUMOR METASTASIS INHIBITORS Chugai Seiyaku Kabushiki Kaisha (JP) 1998-10-14 EP disclosed
EP-0764443-A1 AMELIORANT OR REMEDY FOR PARANEOPLASTIC SYNDROME Chugai Seiyaku Kabushiki Kaisha (JP) 1997-03-26 EP disclosed
EP-0755922-A1 22-THIAVITAMIN D 3 DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1997-01-29 EP disclosed
EP-0521550-B1 Vitamin D compound, method of preparing this compound and intermediate therefor DUPHAR INT RES (NL) 1996-09-18 EP disclosed