SCHEMBL27031828

SCHEMBL27031828

C[C@@H](O)CN1CCN(c2ncc(Oc3cc(CN4CCC(CNC(=O)O)CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21550710 1.00 FURIN (0.84) FURIN
SCHEMBL21551350 0.94 FURIN (0.82) FURIN
SCHEMBL21551349 0.94 FURIN (0.82) FURIN
SCHEMBL29927885 0.94 FURIN (0.82) FURIN
SCHEMBL24872468 0.94 FURIN (0.81) FURIN
SCHEMBL23364187 0.94 FURIN (0.81) FURIN
SCHEMBL23364086 0.93 FURIN (0.82) FURIN
SCHEMBL21553780 0.93 FURIN (0.80) FURIN
SCHEMBL29928725 0.93 FURIN (0.80) FURIN
SCHEMBL21553779 0.93 FURIN (0.80) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP claimed
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