SCHEMBL27032579

SCHEMBL27032579

[CH2]C1CCN(Cc2cc(Oc3cnc(N4CCN(CCO)CC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27032408 0.91 FURIN (0.78) FURIN
SCHEMBL21550805 0.89 FURIN (1.00) FURIN
SCHEMBL29928665 0.89 FURIN (1.00) FURIN
SCHEMBL27032331 0.88 FURIN (0.81) FURIN
SCHEMBL28538186 0.88 FURIN (0.81) FURIN
SCHEMBL27032102 0.87 FURIN (0.62) FURIN
SCHEMBL21553757 0.87 FURIN (0.86) FURIN
SCHEMBL27032447 0.87 FURIN (0.78) FURIN
SCHEMBL27032312 0.87 FURIN (0.82) FURIN
SCHEMBL21551040 0.87 FURIN (0.80) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP claimed
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