SCHEMBL27032722

SCHEMBL27032722

CS(=O)(=O)OCc1cc(Oc2cnc(N3CCCN(C(=O)O)CC3)nc2)nc(-c2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551306 0.91 FURIN (0.52) FURIN
SCHEMBL29890774 0.90 FURIN (0.52) FURIN
SCHEMBL21551403 0.90 FURIN (0.52) FURIN
SCHEMBL26077209 0.89 FURIN (0.54) FURIN
SCHEMBL26077213 0.89 FURIN (0.54) FURIN
SCHEMBL21551698 0.88 FURIN (0.60) FURIN
SCHEMBL21550924 0.87 FURIN (0.62) FURIN
SCHEMBL29891051 0.87 FURIN (0.52) FURIN
SCHEMBL21551750 0.87 FURIN (0.52) FURIN
SCHEMBL21551387 0.86 FURIN (0.55) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
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