Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27129316 | 0.92 | CYP1A2 (0.52) | MAPK1HPGDKDM4CSMN1; SMN2NPSR1 | |
| SCHEMBL31297128 | 0.81 | CYP1A2 (0.46) | MAPK1HPGDSMN1; SMN2NPSR1TSHR | |
| SCHEMBL23754134 | 0.78 | PDE4D (0.50) | MAPK1HPGDSMN1; SMN2NPSR1TSHR | |
| SCHEMBL8803869 | 0.78 | KDM4C (0.54) | MAPK1HPGDKDM4CSMN1; SMN2NPSR1 | |
| SCHEMBL23112442 | 0.77 | KDM4C (0.49) | MAPK1HPGDKDM4CSMN1; SMN2TSHR | |
| SCHEMBL28548519 | 0.77 | KDM4C (0.49) | MAPK1HPGDKDM4CSMN1; SMN2GAA | |
| SCHEMBL23112395 | 0.74 | KDM4E (0.48) | MAPK1HPGDSMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL23112514 | 0.73 | KDM4C (0.61) | MAPK1HPGDKDM4CSMN1; SMN2NPSR1 | |
| SCHEMBL508530 | 0.71 | PDE4D (0.53) | MAPK1HPGDSMN1; SMN2TSHRMEN1 | |
| SCHEMBL29603884 | 0.71 | KDM4C (0.49) | MAPK1HPGDKDM4CNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119233974-A | Indolone derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| WO-2024017372-A1 | INDOLONE DERIVATIVE AND USE THEREOF | 成都百裕制药股份有限公司 | 2024-01-25 | — | — | WO | disclosed |