SCHEMBL270380

SCHEMBL270380

[CH2]CC(C)(O)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2745680 0.82
SCHEMBL23931 0.78
SCHEMBL11664101 0.75
SCHEMBL357212 0.75
Ammonia Solution, Strong SCHEMBL441052 0.74
SCHEMBL10821853 0.74
Tert-Butanol SCHEMBL11220086 0.74 TSHR (0.43)
Hydrochloric Acid SCHEMBL28719957 0.74
SCHEMBL12479851 0.74
SCHEMBL1614263 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4750713-B2 2011-08-17 JP claimed
JP-4717005-B2 2011-07-06 JP claimed
JP-4717006-B2 2011-07-06 JP claimed
US-7595345-B2 Vitamin D receptor modulators ELI LILLY AND COMPANY (US) 2009-09-29 US claimed
US-20080200552-A1 Vitamin D Receptor Modulators ELI LILLY AND COMPANY (IN) 2008-08-21 US claimed
EP-1692123-B1 PHENYL-FURAN COMPOUNDS AS VITAMIN D RECEPTOR MODULATORS LILLY CO ELI (US) 2008-05-28 EP claimed
EP-1687292-B1 VITAMIN D RECEPTOR MODULATORS LILLY CO ELI (US) 2007-08-22 EP claimed
US-20070149810-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY (US) 2007-06-28 US claimed
JP-2007512326-A 2007-05-17 JP claimed
US-20070106095-A1 Vitamin d receptor modulators ELI LILLY AND COMPANY 2007-05-10 US claimed
WO-2005051898-A2 VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-09 WO claimed
WO-2005051936-A1 PHENYL-FURAN COMPOUNDS AS VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-09 WO claimed
WO-2005051893-A2 VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-09 WO claimed
WO-2005051940-A2 VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-09 WO claimed
WO-2005051938-A1 VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-06-09 WO claimed
EP-0344288-B1 METHOD OF INHIBITING THE ACTIVITY OF LEUKOCYTE DERIVED CYTOKINES HOECHST ROUSSEL PHARMA (US) 1995-02-15 EP claimed
US-5214074-A Unsaturated compound for controlling curing reaction such that it takes place at the same rate as decomposition of foaming agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-25 US claimed
EP-0344288-A4 METHOD OF INHIBITING THE ACTIVITY OF LEUKOCYTE DERIVED CYTOKINES 1992-01-15 EP claimed
EP-0344288-A1 METHOD OF INHIBITING THE ACTIVITY OF LEUKOCYTE DERIVED CYTOKINES HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-12-06 EP claimed
WO-1989005145-A1 METHOD OF INHIBITING THE ACTIVITY OF LEUKOCYTE DERIVED CYTOKINES HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-06-15 WO claimed