Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893905 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL3103111 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL28036830 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL3804921 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL4015850 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL21439803 | 1.00 | MAPT (0.54) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL17927927 | 0.98 | MAPT (0.52) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL4016679 | 0.98 | MAPT (0.50) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL5975672 | 0.96 | MAPT (0.48) | MAPTABCC4FOLH1ALDH1A1USP2 | |
| SCHEMBL3779386 | 0.91 | ABCC4 (0.46) | MAPTABCC4FOLH1ALDH1A1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213493-A1 | NANOMATERIALS COMPRISING TRIOLS | BEAM THERAPEUTICS INC. | 2025-07-03 | — | — | US | disclosed |
| US-12296053-B2 | Nanomaterials comprising triols | BEAM THERAPEUTICS INC. (US) | 2025-05-13 | — | — | US | disclosed |
| EP-4540222-A1 | NANOMATERIALS COMPRISING TRIOLS | Beam Therapeutics Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119698406-A | Nanomaterials comprising triols | 比姆医疗股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025038855-A1 | IONIZABLE LIPIDS WITH BRANCHED HEAD GROUPS | BEAM THERAPEUTICS INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| US-20240252443-A1 | NANOMATERIALS COMPRISING TRIOLS | BEAM THERAPEUTICS INC. | 2024-08-01 | — | — | US | disclosed |
| WO-2024019936-A1 | NANOMATERIALS COMPRISING TRIOLS | BEAM THERAPEUTICS INC. (US) | 2024-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252443-A1 | NANOMATERIALS COMPRISING TRIOLS | PNPLA2, LIPA, PHOSPHO1 | MAPT 893/4885ABCC4 726/4885FOLH1 3161/4885 |
| US-12296053-B2 | Nanomaterials comprising triols | PNPLA2, LIPA, PHOSPHO1 | MAPT 893/4885ABCC4 726/4885FOLH1 3161/4885 |
| US-20250213493-A1 | NANOMATERIALS COMPRISING TRIOLS | PNPLA2, LIPA, PHOSPHO1 | MAPT 893/4885ABCC4 726/4885FOLH1 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.