⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763610 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL13679461 | 0.77 | — | — | |
| SCHEMBL6083123 | 0.77 | — | — | |
| SCHEMBL2138136 | 0.77 | — | — | |
| SCHEMBL2138137 | 0.77 | — | — | |
| SCHEMBL4655169 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL15540205 | 0.73 | — | — | |
| SCHEMBL38447 | 0.71 | — | — | |
| SCHEMBL30968861 | 0.71 | — | — | |
| SCHEMBL108436 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179653-A1 | REDOX REVERSIBLE FLUORESCENT PROBE AND PERFORMING SINGLE-ELECTRON TRANSFER FLUORESCENCE PROBING | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE | 2021-06-17 | — | — | US | disclosed |
| CN-111039774-A | Process for producing aliphatic carboxylic acid compound and pyridine compound adduct of aliphatic ketone compound | 捷恩智株式会社 | 2020-04-21 | — | — | CN | disclosed |
| EP-1888509-B1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-8133851-B2 | Heteroaroyl-substituted serine amides | BASF SE (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20110318470-A1 | Method For Improving Plant Health | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110209253-A1 | Method for Improving Plant Health | BASF SE (DE) | 2011-08-25 | — | — | US | disclosed |
| EP-2348841-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-2348849-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-7879761-B2 | Herbicides; 1-{Methylcarbamoyl-[(1-methyl-3-trifluoromethyl-1H-pyrazol-4-carbonyl)amino]methyl}-allyl acetate; acylation of keto compounds and reduction of the ketone, or the serine derivative is reacted with a heteroaryl acid and then with a secondary or tertiary amine | BASF AKTIENGESELLSCHAFT (DE) | 2011-02-01 | — | — | US | disclosed |
| EP-2121583-B1 | HETEROARYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-6833481-B2 | Catalytic dehydrative isomerization | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-12-21 | — | — | US | disclosed |
| US-20040158064-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2004-08-12 | — | — | US | disclosed |
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2003-12-04 | — | — | US | disclosed |
| US-20030109755-A1 | Process for producing 2-alkyl-2cyclopentenones | TAKASAGO INTERNATIONAL CORPORATION | 2003-06-12 | — | — | US | disclosed |
| EP-1316541-A1 | Process for producing 2-alkyl-2-cyclopentenones | Takasago International Corporation (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-03-07 | — | — | US | disclosed |
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307047-B1 | PYRIDAZINONE COMPOUNDS; INHIBITORS OF CYCLOOXYGENASE-2 (COX-2); SELECTIVITY OF THESE COMPOUNDS FOR COX-2 MINIMIZES THE UNWANTED GI AND RENAL SIDE-EFFECTS SEEN WITH CURRENTLY MARKETED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ABBOTT LABORATORIES | 2001-10-23 | — | — | US | disclosed |
| EP-1007515-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | Abbott Laboratories (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010331-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 1999-03-04 | — | — | WO | disclosed |