SCHEMBL27058129

SCHEMBL27058129

CN1CCCN(c2cnc(Oc3cc(CN4CCC(CC(=O)O)CC4)cc(-c4cc(I)cc(I)c4)n3)cn2)CC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29928292 0.92 FURIN (1.00) FURIN
SCHEMBL21551155 0.92 FURIN (1.00) FURIN
SCHEMBL21551287 0.88 FURIN (1.00) FURIN
SCHEMBL29927822 0.88 FURIN (1.00) FURIN
SCHEMBL21551208 0.84 FURIN (0.85) FURIN
SCHEMBL29928266 0.84 FURIN (0.85) FURIN
SCHEMBL21551638 0.83 FURIN (0.83) FURIN
SCHEMBL29928789 0.83 FURIN (0.83) FURIN
SCHEMBL21551250 0.81 FURIN (0.82) FURIN
SCHEMBL29928834 0.81 FURIN (0.82) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
Send feedback