Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769742 | 1.00 | IRAK4 (0.34) | IRAK4ATRATRIPPDE10APARP1 | |
| SCHEMBL30769520 | 0.97 | IRAK4 (0.36) | IRAK4ATRATRIPPDE10AHTR2B | |
| SCHEMBL30769968 | 0.91 | PDE10A (0.36) | IRAK4ATRATRIPPDE10APARP1 | |
| SCHEMBL30769800 | 0.91 | IRAK4 (0.33) | IRAK4ATRATRIPPDE10A | |
| SCHEMBL27059758 | 0.85 | CCNT1 (0.41) | IRAK4ATRATRIPPARP1HTR2B | |
| SCHEMBL30769965 | 0.85 | PARP1 (0.37) | PARP1CDK9 | |
| SCHEMBL32664786 | 0.84 | ATR (0.36) | ATRPARP1 | |
| SCHEMBL27059126 | 0.82 | CCNT1 (0.43) | IRAK4ATRATRIPPARP1HTR2B | |
| SCHEMBL30769756 | 0.82 | PARP1 (0.31) | PARP1HTR2B | |
| SCHEMBL30769850 | 0.81 | PARP1 (0.41) | PARP1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |