⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1004927 | 0.97 | — | — | |
| SCHEMBL22142421 | 0.89 | — | — | |
| SCHEMBL20369068 | 0.82 | — | — | |
| SCHEMBL6393533 | 0.82 | — | — | |
| SCHEMBL19775401 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL31320001 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL22655784 | 0.80 | — | — | |
| Iodide SCHEMBL9023394 | 0.80 | — | — | |
| SCHEMBL29889 | 0.75 | — | — | |
| SCHEMBL11760890 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188805-B1 | 1,3-DITHIOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| EP-0188805-A1 | 1,3-Dithiole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | claimed |
| US-20240425498-A1 | PARG INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2024-12-26 | — | — | US | disclosed |
| EP-4413001-A1 | PARG INHIBITORY COMPOUNDS | FoRx Therapeutics AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| US-20240228486-A1 | SULFONE- AND SULFOXIMINE-BASED SELECTIVE PARP1 INHIBITORS | ENLIVEN INC (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240217990-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2024-07-04 | — | — | US | disclosed |
| CN-118055934-A | PARG inhibitory compounds | 福克斯治疗股份公司 | 2024-05-17 | — | — | CN | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023220141-A1 | INHIBITORS OF GLUTATHIONE S-TRANSFERASE ZETA 1 (GSTZ1) AND METHODS OF USE | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023215801-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023215775-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2006024741-A2 | HYBRID QA MOLECULES WHEREIN Q IS AN AMINOQUINOLINE AND A IS AN ANTIBIOTIC RESIDUE, THEIR SYNTHESIS AND THEIR USES AS ANTIBACTERIAL AGENT | PALUMED S.A. (FR) | 2006-03-09 | — | — | WO | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| EP-1159263-A1 | NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050391-A1 | NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF | MERCK & CO., INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0946517-A1 | N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION | SYNTHELABO (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998022443-A1 | N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION | SYNTHELABO (FR) | 1998-05-28 | — | — | WO | disclosed |
| EP-0188805-B1 | 1,3-DITHIOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-4737494-A | 2-YLIDENE AMMONIUM COMPOUNDS USED IN TREATING LIVER DISEASES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0188805-A1 | 1,3-Dithiole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |