Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256112 | 0.83 | USP2 (0.31) | USP2 | |
| SCHEMBL18256175 | 0.83 | USP2 (0.31) | USP2 | |
| SCHEMBL18256117 | 0.83 | USP2 (0.31) | USP2 | |
| SCHEMBL81761 | 0.80 | — | — | |
| SCHEMBL25821020 | 0.77 | — | — | |
| SCHEMBL25821022 | 0.77 | — | — | |
| SCHEMBL24615651 | 0.74 | — | — | |
| SCHEMBL25801664 | 0.74 | — | — | |
| SCHEMBL12826305 | 0.73 | USP2 (0.36) | USP2 | |
| SCHEMBL23230045 | 0.72 | USP2 (0.35) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873903-B1 | SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS AS HPK1 INHIBITORS | GILEAD SCIENCES INC (US) | 2024-01-24 | — | — | EP | disclosed |