SCHEMBL27064809

SCHEMBL27064809

CC(C)(C)OC(=O)Nc1cccc2c1ccc1occ(C3CCC(=O)NC3=O)c12

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 18/20 0.44
CRBN Q96SW2 18/20 0.44
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323524 0.84 DDB1 (0.46) DDB1CRBN
SCHEMBL24754291 0.83 DDB1 (0.42) DDB1CRBN
SCHEMBL23918314 0.83 CA12 (0.43) DDB1CRBNCA12CA1CA9
SCHEMBL23634911 0.83 CA12 (0.43) DDB1CRBNCA12CA1CA9
SCHEMBL23918313 0.83 CA12 (0.43) DDB1CRBNCA12CA1CA9
SCHEMBL29323451 0.79 CYP2C19 (0.48) DDB1CRBN
SCHEMBL24939665 0.79 CA12 (0.49) DDB1CRBNCA12CA1CA9
SCHEMBL24950362 0.79 CA12 (0.44) DDB1CRBNCA12CA1CA9
SCHEMBL29323527 0.78 KDM4E (0.38) DDB1CRBN
SCHEMBL23635028 0.77 DDB1 (0.46) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed
EP-4310083-A1 FURAN FUSED RING-SUBSTITUTED GLUTARIMIDE COMPOUND Medshine Discovery Inc. (CN) 2024-01-24 EP disclosed