⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462740 | 0.85 | — | — | |
| SCHEMBL23108586 | 0.84 | — | — | |
| SCHEMBL23114657 | 0.84 | — | — | |
| SCHEMBL23102810 | 0.84 | — | — | |
| SCHEMBL23107230 | 0.84 | — | — | |
| SCHEMBL23108592 | 0.84 | — | — | |
| SCHEMBL14818609 | 0.75 | — | — | |
| SCHEMBL18968087 | 0.73 | — | — | |
| SCHEMBL29299357 | 0.73 | — | — | |
| SCHEMBL18969350 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |