Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.51 |
| ▸ | CBL | P22681 | 16/20 | 0.51 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32666900 | 1.00 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL27068755 | 0.94 | CBLB (0.45) | CBLBCBLCBLC | |
| SCHEMBL27067925 | 0.89 | CBLB (0.54) | CBLBCBL | |
| SCHEMBL32666734 | 0.89 | CBLB (0.54) | CBLBCBL | |
| SCHEMBL27067947 | 0.88 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL27068754 | 0.88 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL32666686 | 0.88 | CBLB (0.51) | CBLBCBLCBLC | |
| SCHEMBL27067924 | 0.88 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL32667046 | 0.87 | CBLB (0.51) | CBLBCBL | |
| SCHEMBL32667103 | 0.87 | CBLB (0.51) | CBLBCBLCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |