Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 16/20 | 0.39 |
| ▸ | CBL | P22681 | 11/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27068170 | 0.94 | CBLB (0.40) | CBLBCBLBRD4HTR1AHTR1B | |
| SCHEMBL27068115 | 0.93 | CBLB (0.39) | CBLBCBL | |
| SCHEMBL32667149 | 0.91 | CBLB (0.38) | CBLBCBL | |
| SCHEMBL27068109 | 0.91 | CBLB (0.39) | CBLBCBL | |
| SCHEMBL27069833 | 0.90 | CBLB (0.41) | CBLBCBLBRD4 | |
| SCHEMBL30728164 | 0.89 | CBLB (0.47) | CBLBCBL | |
| SCHEMBL27068119 | 0.87 | CBLB (0.40) | CBLBCBLBRD4 | |
| SCHEMBL27068036 | 0.87 | CBLB (0.49) | CBLBCBL | |
| SCHEMBL27068163 | 0.86 | CBLB (0.39) | CBLBCBLBRD4 | |
| SCHEMBL27068161 | 0.86 | CBLB (0.39) | CBLBCBLHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |