Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 14/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CBL | P22681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667133 | 0.92 | CBLB (0.40) | CBLBBRD4HRH3KCNH2CBL | |
| SCHEMBL30728232 | 0.90 | CBLB (0.48) | CBLBCBL | |
| SCHEMBL27068276 | 0.90 | CBLB (0.39) | CBLBHRH3KCNH2CBL | |
| SCHEMBL30728175 | 0.90 | CBLB (0.39) | CBLBHRH3KCNH2CBL | |
| SCHEMBL30728197 | 0.89 | CBLB (0.40) | CBLBBRD4CBL | |
| SCHEMBL27068194 | 0.89 | CBLB (0.40) | CBLBBRD4CBL | |
| SCHEMBL27068278 | 0.89 | CBLB (0.35) | CBLBBRD4HRH3KCNH2 | |
| SCHEMBL27041435 | 0.85 | CBLB (0.36) | CBLBCBL | |
| SCHEMBL27068277 | 0.84 | BRD4 (0.36) | CBLBBRD4CBL | |
| SCHEMBL30728164 | 0.84 | CBLB (0.47) | CBLBCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028336-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-01-29 | — | — | US | disclosed |
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028336-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | CBLB, CBL, CBLC | CBLB 1/4885BRD4 2268/4885HRH3 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.