⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538323 | 0.87 | — | — | |
| SCHEMBL19565538 | 0.82 | — | — | |
| SCHEMBL19565535 | 0.82 | — | — | |
| SCHEMBL19565523 | 0.82 | — | — | |
| SCHEMBL19565540 | 0.82 | — | — | |
| SCHEMBL19565539 | 0.82 | — | — | |
| SCHEMBL14134601 | 0.80 | — | — | |
| SCHEMBL12113356 | 0.74 | CYP2A6 (0.33) | — | |
| SCHEMBL12379124 | 0.74 | — | — | |
| SCHEMBL12417870 | 0.74 | EPHX1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475783-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-25 | — | — | US | disclosed |
| US-9427425-B2 | Extracts, fractions and compositions comprising acetogenins and their applications | LAILA NUTRACEUTICALS (IN) | 2016-08-30 | — | — | US | disclosed |
| US-20160214988-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | SILICON VALLEY BANK | 2016-07-28 | — | — | US | disclosed |
| US-20150191420-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-20150031694-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-01-29 | — | — | US | disclosed |
| US-8865736-B2 | Antibacterial agents | Biota Scientific Pty Ltd (AU) | 2014-10-21 | — | — | US | disclosed |
| US-20140056987-A1 | COMPOSITIONS COMPRISING EXTRACTS OR FRACTIONS DERIVED FROM ANNONA SQUAMOSA FOR THE PREVENTION, TREATMENT OR CONTROL OF INFLAMMATORY AND METABOLIC DISORDERS | LAILA NUTRACEUTICALS (IN) | 2014-02-27 | — | — | US | disclosed |
| US-20130072520-A2 | ANTIBACTERIAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-03-21 | — | — | US | disclosed |
| EP-1425318-B1 | ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS | VERSALIS SPA (IT) | 2013-01-16 | — | — | EP | disclosed |
| US-20120201884-A1 | EXTRACTS, FRACTIONS AND COMPOSITIONS COMPRISING ACETOGENINS AND THEIR APPLICATIONS | LAlLA NUTRACEUTICALS (IN) | 2012-08-09 | — | — | US | disclosed |
| US-20120122918-A1 | ANTIBACTERIAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-05-17 | — | — | US | disclosed |
| US-8088791-B2 | Antibacterial agents | Biots Scientific Management Pty Ltd (AU) | 2012-01-03 | — | — | US | disclosed |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2010-07-08 | — | — | US | disclosed |
| US-7081505-B2 | Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds | POLIMERI EUROPA S.P.A. (IT) | 2006-07-25 | — | — | US | disclosed |
| US-20040198934-A1 | Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds | POLIMERI EUROPA S.P.A. (IT) | 2004-10-07 | — | — | US | disclosed |
| EP-1425318-A1 | ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS | Polimeri Europa S.p.A. (IT) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003010210-A1 | ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS | POLIMERI EUROPA S.P.A. (IT) | 2003-02-06 | — | — | WO | disclosed |
| US-6274529-B1 | COORDINATION CATALYST CONTAINS METALLOCENE OF HAFNIUM, TITANIUM, OR ZIRCONIUM, AND HETEROCOMPOUND CONTAINING OXYGEN, NITROGEN, SULFUR, AND/OR PHOSPHORUS | ENICHEM S.P.A. (IT) | 2001-08-14 | — | — | US | disclosed |
| EP-0771822-A1 | Catalytic system for the (co)polymerization of alpha-olefins | ENICHEM S.p.A. (IT) | 1997-05-07 | — | — | EP | disclosed |