Cefpodoxime Proxetil

Cefpodoxime Proxetil

SCHEMBL27071

COCC1=C(C(=O)OC(C)OC(=O)OC(C)C)N2C(=O)[C@@H](NC(=O)/C(=N\OC)c3csc(N)n3)[C@H]2SC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Cefpodoxime Proxetil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 1.00
ABCB11 O95342 1/20 1.00
PDE4D Q08499 1/20 1.00
NR1I2 O75469 6/20 0.75
HTR2C P28335 1/20 0.75
MAPT P10636 3/20 0.66
PPARG P37231 2/20 0.66
SLC22A6 Q4U2R8 2/20 0.66
SLC22A8 Q8TCC7 2/20 0.66
SLC22A11 Q9NSA0 2/20 0.66
ALB P02768 1/20 0.66
TDP1 Q9NUW8 4/20 0.65
APEX1 P27695 2/20 0.65
HSD17B10 Q99714 2/20 0.65
CYP1A2 P05177 1/20 0.65
PKM P14618 1/20 0.65
ALDH1A1 P00352 1/20 0.65
ABCC4 O15439 1/20 0.65
LMNA P02545 1/20 0.65
POLB P06746 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cefpodoxime Proxetil SCHEMBL4410291 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL29465200 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL6136644 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL8687125 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL379709 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL614583 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL7256264 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL7810065 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL22330291 1.00 PTGS1 (1.00) PTGS1ABCB11PDE4DNR1I2HTR2C
Cefpodoxime Proxetil SCHEMBL5266189 0.99 PTGS1 (0.99) PTGS1ABCB11PDE4DNR1I2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9196 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA ATOPIC MEDICAL INC (US) 2026-01-29 US claimed
EP-3452124-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-10-08 EP claimed
EP-3452123-B1 HEMOSTATIC DEVICES AND METHODS OF USE MEDTRONIC INC (US) 2025-09-24 EP claimed
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 US claimed
US-12343430-B2 Methods of improving pharmaceutical substance solubilization and products thereof MUDANJIANG LINRUN PHARAMA EXCIPIENTS LLC. (CN) 2025-07-01 US claimed
EP-3230500-B1 METHODS OF ORIENTING MULTIFILAMENT YARN AND MONOFILAMENTS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS THEREOF TEPHA INC (US) 2025-06-18 EP claimed
EP-4566590-A1 TASTE-MASKING MICROSPHERE, PREPARATION PROCESS THEREFOR, AND USE THEREOF Harbin Kanon Pharmaceutical Co., Ltd (CN) 2025-06-11 EP claimed
CN-222875458-U Paper feeding mechanism of automatic box sticking machine 汕头市万腾纸业有限公司 2025-05-16 CN claimed
CN-119350367-B Preparation process of cefpodoxime mother nucleus 7-AMCA 山东鑫泉医药有限公司 2025-04-29 CN claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0680322-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CLAVULANIC ACID ALONE OR IN COMBINATION WITH OTHER BETA-LACTAM ANTIBIOTICS SMITHKLINE BEECHAM PLC (GB) 1995-11-08 EP claimed
EP-0678095-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-10-25 EP claimed
WO-1995012601-A1 CRYSTALLINE PENICILLIN DERIVATIVE, AND ITS PRODUCTION AND USE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1995-05-11 WO claimed
US-5409917-A Topical treatment of acne with cephalosporins Towsend, Marvin S. (US) 1995-04-25 US claimed
WO-1994016696-A1 PHARMACEUTICAL FORMULATIONS COMPRISING CLAVULANIC ACID ALONE OR IN COMBINATION WITH OTHER BETA-LACTAM ANTIBIOTICS SMITHKLINE BEECHAM PLC (GB) 1994-08-04 WO claimed
EP-0141977-B1 STARCH BREAD SOCIETE DES PRODUITS NESTLE S.A. (CH) 1988-01-13 EP claimed
EP-0141977-A1 Starch bread SOCIETE DES PRODUITS NESTLE S.A. (CH) 1985-05-22 EP claimed