Lithium Ion

Lithium Ion

SCHEMBL270739

[Li+].[MgH2].[NH2-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL24633 0.82
Lithium Ion SCHEMBL516186 0.82
Lithium Ion SCHEMBL11581737 0.67
Lithium Ion SCHEMBL3381113 0.67
SCHEMBL5962031 0.67
Fluoride Ion SCHEMBL18864377 0.67
SCHEMBL3117819 0.67
Lithium Ion SCHEMBL4520287 0.67
SCHEMBL3128306 0.67
Lithium Ion SCHEMBL3475789 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360161-B1 Preparation and use of magnesium amides MUNICHEM GMBH (DE) 2016-08-31 EP disclosed
US-8134005-B2 Preparation and use of magnesium amides Ludwig-Maximilians-Universitat München (DE) 2012-03-13 US disclosed
EP-2360161-A1 Preparation and use of magnesium amides Ludwig-Maximilians-Universität München (DE) 2011-08-24 EP disclosed
EP-1981893-B1 PREPARATION AND USE OF MAGNESIUM AMIDES UNIV MUENCHEN L MAXIMILIANS (DE) 2011-06-08 EP disclosed
US-20100144516-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2010-06-10 US disclosed
EP-2142556-A1 PREPARATION AND USE OF MAGNESIUM AMIDES Ludwig-Maximilians-Universität München (DE) 2010-01-13 EP disclosed
CN-101622260-A The preparation of magnesium amides and purposes UNIV MUENCHEN L MAXIMILIANS 2010-01-06 CN disclosed
US-20090176988-A1 Preparation and Use of Magnesium Amides LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) 2009-07-09 US disclosed
EP-1981893-A1 PREPARATION AND USE OF MAGNESIUM AMIDES Ludwig-Maximilians-Universität München (DE) 2008-10-22 EP disclosed
WO-2008087057-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2008-07-24 WO disclosed
WO-2007082911-A1 PREPARATION AND USE OF MAGNESIUM AMIDES LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2007-07-26 WO disclosed
EP-1810974-A1 Preparation and use of magnesium amides Ludwig-Maximilians-Universität München (DE) 2007-07-25 EP disclosed