Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 8/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27074410 | 0.89 | LATS1 (0.42) | JAK2TP53MAPTMAPK1KDM4E | |
| SCHEMBL27074418 | 0.89 | ABCG2 (0.43) | KDM1AJAK2KDM4CCHEK1 | |
| SCHEMBL27074404 | 0.87 | JAK2 (0.48) | JAK2CHEK1JAK1 | |
| SCHEMBL27074411 | 0.86 | LATS1 (0.45) | JAK2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27075673 | 0.82 | KDM4C (0.43) | KDM1AJAK2KDM4CTP53MAPT | |
| SCHEMBL27074415 | 0.81 | JAK2 (0.38) | JAK2MAPK1CYP1A2CHEK1JAK1 | |
| SCHEMBL27074407 | 0.81 | CSNK2A1 (0.46) | JAK2MAPTMAPK1SMN1; SMN2TSHR | |
| SCHEMBL27074406 | 0.80 | IDO1 (0.42) | JAK2KDM4CCHEK1 | |
| SCHEMBL27074405 | 0.79 | PIM1 (0.52) | CHEK1 | |
| SCHEMBL27074417 | 0.79 | CSNK2A1 (0.44) | JAK2KDM4CCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | claimed |
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | CKS2, CDK2, PNKP | KDM1A 3110/4885JAK2 73/4885KDM4C 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.