Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.61 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29173188 | 0.94 | EGFR (0.61) | EGFRMETALKINSRKCNH2 | |
| SCHEMBL27076173 | 0.94 | EGFR (0.61) | EGFRMETALKINSRKCNH2 | |
| SCHEMBL30014168 | 0.94 | EGFR (0.61) | EGFRMETALKINSRKCNH2 | |
| SCHEMBL27076030 | 0.88 | EGFR (0.74) | EGFRMETALKINSRKCNH2 | |
| SCHEMBL27076117 | 0.82 | ALK (0.65) | EGFRMETALKINSRKCNH2 | |
| SCHEMBL27075996 | 0.80 | EGFR (0.64) | EGFRMETALK | |
| SCHEMBL30015598 | 0.79 | EGFR (0.76) | EGFRMETALKKCNH2IGF1R | |
| SCHEMBL27076099 | 0.79 | EGFR (0.76) | EGFRMETALKKCNH2IGF1R | |
| SCHEMBL27076019 | 0.79 | EGFR (0.74) | EGFRMETALK | |
| SCHEMBL27076011 | 0.79 | EGFR (0.63) | EGFRMETALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313969-A1 | N2-PHENYLPYRIMIDINE-2,4-DIAMINE COMPOUNDS, AND PREPARATION METHODS AND METHODS OF USE THEREOF | Bridge Biotherapeutics, Inc. (KR) | 2024-02-07 | — | — | EP | disclosed |