Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015407 | 1.00 | EGFR (0.55) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL27076045 | 0.92 | EGFR (0.56) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL27076040 | 0.90 | EGFR (0.58) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL30015267 | 0.89 | EGFR (0.58) | EGFRALKINSRIGF1RZAP70 | |
| SCHEMBL27075983 | 0.89 | EGFR (0.58) | EGFRALKINSRIGF1RZAP70 | |
| SCHEMBL27076077 | 0.88 | EGFR (0.60) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL30015471 | 0.88 | EGFR (0.63) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL27075989 | 0.88 | EGFR (0.63) | EGFRALKLRRK2INSRIGF1R | |
| SCHEMBL30014736 | 0.88 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL27075991 | 0.88 | EGFR (0.61) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313969-A1 | N2-PHENYLPYRIMIDINE-2,4-DIAMINE COMPOUNDS, AND PREPARATION METHODS AND METHODS OF USE THEREOF | Bridge Biotherapeutics, Inc. (KR) | 2024-02-07 | — | — | EP | disclosed |
| CN-117203199-A | N2-phenylpyrimidine-2, 4-diamine compounds, methods of making and using the same | 毕利吉生物科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |