Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 16/20 | 0.46 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29983870 | 0.93 | CD274 (0.44) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29983317 | 0.90 | CD274 (0.52) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27079856 | 0.90 | CD274 (0.52) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29143917 | 0.86 | CD274 (0.52) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27081086 | 0.86 | PDCD1 (0.54) | CD274PDCD1 | |
| SCHEMBL27079454 | 0.81 | CD274 (0.59) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL29983043 | 0.81 | CD274 (0.59) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27082253 | 0.80 | CD274 (0.42) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL30836288 | 0.79 | CD274 (0.57) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL30836341 | 0.79 | CD274 (0.46) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313968-A2 | SUBSTITUTED 1-ARYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1,1'-BIHETEROARYL COMPOUNDS, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2024-02-07 | — | — | EP | disclosed |