⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527394 | 0.97 | — | — | |
| SCHEMBL18420879 | 0.75 | — | — | |
| SCHEMBL4663625 | 0.73 | — | — | |
| SCHEMBL17866117 | 0.73 | — | — | |
| SCHEMBL17866116 | 0.73 | — | — | |
| SCHEMBL28549828 | 0.73 | — | — | |
| SCHEMBL5304841 | 0.69 | — | — | |
| SCHEMBL1481934 | 0.69 | — | — | |
| SCHEMBL833661 | 0.65 | — | — | |
| SCHEMBL833660 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160184340-A1 | THE USE OF SPINOSYNS AND SPINOSYN COMPOSITIONS AS LOCAL ANESTHETICS AND AS ANTIARRHYTHMIC AGENTS | KRITIKOU, CHRISTINE (ONE-THIRD INTEREST) (GR) | 2016-06-30 | — | — | US | disclosed |
| EP-2445506-A1 | THE USE OF SPINOSYNS AND SPINOSYN COMPOSITIONS AGAINST DISEASES CAUSED BY PROTOZOANS, VIRAL INFECTIONS AND CANCER | Entarco SA (GR) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010150100-A1 | THE USE OF SPINOSYNS AND SPINOSYN COMPOSITIONS AGAINST DISEASES CAUSED BY PROTOZOANS, VIRAL INFECTIONS AND CANCER | ENTARCO SA (GR) | 2010-12-29 | — | — | WO | disclosed |
| EP-1423355-A1 | BRIDGED P-PHENYLENEDIAMINES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003024917-A1 | BRIDGED P-PHENYLENEDIAMINES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-03-27 | — | — | WO | disclosed |