Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 11/20 | 0.72 |
| ▸ | MERTK | Q12866 | 11/20 | 0.69 |
| ▸ | AXL | P30530 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626158 | 0.86 | TYRO3 (0.73) | TYRO3MERTKAXL | |
| SCHEMBL30874316 | 0.84 | TYRO3 (0.74) | TYRO3MERTKAXL | |
| SCHEMBL29625545 | 0.84 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19377506 | 0.84 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL29626210 | 0.83 | TYRO3 (0.72) | TYRO3MERTKAXL | |
| SCHEMBL29626265 | 0.82 | TYRO3 (0.71) | TYRO3MERTKAXL | |
| SCHEMBL19377712 | 0.82 | MERTK (0.72) | TYRO3MERTKAXL | |
| SCHEMBL19377570 | 0.82 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19377713 | 0.81 | MERTK (1.00) | TYRO3MERTKAXL | |
| SCHEMBL30672037 | 0.81 | TYRO3 (0.82) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4321513-A2 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | Incyte Corporation (US) | 2024-02-14 | — | — | EP | disclosed |