Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 19/20 | 0.68 |
| ▸ | AXL | P30530 | 2/20 | 0.50 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626261 | 1.00 | TYRO3 (0.68) | TYRO3AXLMERTK | |
| SCHEMBL27088338 | 1.00 | TYRO3 (0.68) | TYRO3AXLMERTK | |
| SCHEMBL29626200 | 0.94 | TYRO3 (0.67) | TYRO3AXL | |
| SCHEMBL29626185 | 0.94 | TYRO3 (0.67) | TYRO3AXL | |
| SCHEMBL29626162 | 0.92 | TYRO3 (0.62) | TYRO3AXLMERTK | |
| SCHEMBL29626164 | 0.92 | TYRO3 (0.62) | TYRO3AXLMERTK | |
| SCHEMBL29626212 | 0.92 | TYRO3 (0.66) | TYRO3AXLMERTK | |
| SCHEMBL29626101 | 0.92 | TYRO3 (0.66) | TYRO3AXLMERTK | |
| SCHEMBL29626180 | 0.89 | TYRO3 (0.67) | TYRO3AXLMERTK | |
| SCHEMBL29626242 | 0.89 | TYRO3 (0.67) | TYRO3AXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4321513-A2 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | Incyte Corporation (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |