Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 19/20 | 0.68 |
| ▸ | CDK2 | P24941 | 14/20 | 0.68 |
| ▸ | CDK1 | P06493 | 9/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.68 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.68 |
| ▸ | CCND3 | P30281 | 3/20 | 0.68 |
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.64 |
| ▸ | CDK6 | Q00534 | 13/20 | 0.61 |
| ▸ | CDK7 | P50613 | 4/20 | 0.61 |
| ▸ | CDK9 | P50750 | 4/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.58 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631120 | 1.00 | CDK4 (0.68) | CDK4CDK2CDK1CCNB1CCNA2 | |
| Hydrochloric Acid SCHEMBL31371275 | 0.99 | CDK4 (0.67) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL26755385 | 0.89 | CDK4 (0.68) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL26753932 | 0.89 | CDK4 (0.68) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL30631091 | 0.85 | CDK4 (0.63) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL26633437 | 0.85 | CDK4 (0.63) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL28930875 | 0.84 | CDK4 (0.62) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL29019943 | 0.84 | CDK4 (0.60) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL30631113 | 0.84 | CDK4 (0.61) | CDK4CDK2CDK1CCNB1CCNA2 | |
| SCHEMBL26633414 | 0.84 | CDK4 (0.61) | CDK4CDK2CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050577-A1 | CDK INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN (SHANGHAI) PHARMA ENG CO., LTD. (CN) | 2024-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050577-A1 | CDK INHIBITORS AND PHARMACEUTICAL USES THEREOF | CDKL1, CDKL2, CDKL3 | CDK4 13/4885CDK2 9/4885CDK1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.