⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17233229 | 0.91 | — | — | |
| SCHEMBL17233228 | 0.91 | — | — | |
| SCHEMBL2718174 | 0.88 | — | — | |
| SCHEMBL27913781 | 0.88 | — | — | |
| SCHEMBL2718176 | 0.88 | — | — | |
| SCHEMBL23520549 | 0.88 | — | — | |
| SCHEMBL2714838 | 0.88 | — | — | |
| SCHEMBL23412004 | 0.87 | KDM4E (0.33) | — | |
| SCHEMBL30991045 | 0.87 | KDM4E (0.33) | — | |
| SCHEMBL23412007 | 0.87 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051956-A1 | SOS1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2024-02-15 | — | — | US | disclosed |
| EP-4267250-A1 | SOS1 INHIBITORS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022140427-A1 | SOS1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-06-30 | — | — | WO | disclosed |