SCHEMBL27098271

SCHEMBL27098271

Cc1ccc(CC(=O)N(C)CCC(=O)NCCCC[C@H](OC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.43
▸ FOLH1 Q04609 17/20 0.42
▸ LTB4R Q15722 1/20 0.41
▸ LTB4R2 Q9NPC1 1/20 0.41
▸ ALB P02768 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19633767 0.92 FOLH1 (0.46) FOLH1LTB4RLTB4R2ALB
SCHEMBL19633798 0.92 FOLH1 (0.49) FOLH1ALB
SCHEMBL19633768 0.88 ALB (0.50) FOLH1ALB
SCHEMBL27098049 0.88 FOLH1 (0.41) FOLH1ALB
SCHEMBL27098050 0.88 FOLH1 (0.37) FOLH1ALB
SCHEMBL27098048 0.88 FOLH1 (0.37) FOLH1ALB
SCHEMBL27098046 0.88 FOLH1 (0.37) FOLH1ALB
SCHEMBL19633686 0.88 FOLH1 (0.51) TGM2FOLH1
SCHEMBL19633773 0.79 FOLH1 (0.63) FOLH1
SCHEMBL27098294 0.79 FOLH1 (0.50) TGM2FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy THE JOHNS HOPKINS UNIVERSTY (US) 2024-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911488-B2 Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy FOLH1, PSMA3, PSMA7 TGM2 76/4885FOLH1 1/4885LTB4R 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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