Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | IKZF2 | Q9UKS7 | 12/20 | 0.44 |
| ▸ | WIZ | O95785 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26258867 | 0.90 | CRBN (0.60) | CRBNESR1IKZF2WIZ | |
| SCHEMBL26375237 | 0.88 | CRBN (0.47) | CRBNESR1IKZF2WIZ | |
| SCHEMBL20128681 | 0.88 | CRBN (0.51) | CRBNESR1IKZF2WIZ | |
| SCHEMBL27423430 | 0.86 | CRBN (0.51) | CRBNESR1IKZF2WIZ | |
| SCHEMBL21450600 | 0.85 | CRBN (0.50) | CRBNESR1IKZF2WIZ | |
| SCHEMBL26044148 | 0.84 | CRBN (0.58) | CRBNESR1IKZF2WIZ | |
| SCHEMBL26375243 | 0.84 | CRBN (0.47) | CRBNESR1IKZF2WIZ | |
| SCHEMBL27099504 | 0.83 | CRBN (0.61) | CRBN | |
| SCHEMBL29614522 | 0.80 | CRBN (0.63) | CRBNESR1IKZF2WIZ | |
| SCHEMBL20234982 | 0.80 | CRBN (0.63) | CRBNESR1IKZF2WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | CRBN 3/4885ESR1 2710/4885IKZF2 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.