Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22836915 | 0.99 | RAD52 (0.46) | RAD52GSK3BROCK2ROCK1LATS1 | |
| Hydrochloric Acid SCHEMBL22836914 | 0.99 | RAD52 (0.46) | RAD52GSK3BROCK2ROCK1LATS1 | |
| Hydrochloric Acid SCHEMBL30062597 | 0.99 | RAD52 (0.46) | RAD52GSK3BROCK2ROCK1LATS1 | |
| Hydrochloric Acid SCHEMBL30063113 | 0.99 | RAD52 (0.46) | RAD52GSK3BROCK2ROCK1LATS1 | |
| SCHEMBL21098363 | 0.81 | GSK3B (0.42) | RAD52GSK3BROCK2ROCK1LATS1 | |
| SCHEMBL21098364 | 0.81 | GSK3B (0.42) | RAD52GSK3BROCK2ROCK1LATS1 | |
| SCHEMBL5461889 | 0.79 | GSK3B (0.52) | RAD52GSK3BROCK1LATS1HTR2C | |
| SCHEMBL26669231 | 0.79 | GSK3B (0.52) | RAD52GSK3BROCK1LATS1HTR2C | |
| SCHEMBL38663101 | 0.79 | GSK3B (0.52) | RAD52GSK3BROCK1LATS1HTR2C | |
| SCHEMBL5630952 | 0.78 | RAD52 (0.49) | RAD52GSK3BROCK2LATS1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3990442-B1 | RHO KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION INC (US) | 2024-02-28 | — | — | EP | disclosed |