SCHEMBL27105627

SCHEMBL27105627

CNc1cc(C(C)C)nc2c(C(=O)NC3CCC3OC)cnn12

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYK2 P29597 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27105855 1.00 TYK2 (0.63) TYK2
SCHEMBL29990614 0.80 TYK2 (0.64) TYK2
SCHEMBL29990745 0.80 TYK2 (0.64) TYK2
SCHEMBL29990624 0.80 TYK2 (0.64) TYK2
SCHEMBL23583101 0.78 TYK2 (1.00) TYK2
SCHEMBL21285444 0.78 TYK2 (1.00) TYK2
SCHEMBL20688367 0.78 TYK2 (1.00) TYK2
SCHEMBL20688851 0.78 TYK2 (1.00) TYK2
SCHEMBL20689499 0.78 TYK2 (1.00) TYK2
SCHEMBL20687884 0.78 TYK2 (1.00) TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024042361-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2024-02-29 — — WO disclosed
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