Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.72 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5960982 | 0.99 | DPP4 (0.71) | DPP4DPP8DPP9 | |
| SCHEMBL2851946 | 0.90 | DPP4 (0.74) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2708885 | 0.87 | DPP4 (0.67) | DPP4DPP8DPP9 | |
| SCHEMBL2852755 | 0.86 | DPP4 (0.76) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2708597 | 0.84 | DPP4 (0.69) | DPP4DPP8DPP9 | |
| SCHEMBL2873218 | 0.84 | DPP4 (0.75) | DPP4DPP8DPP9 | |
| SCHEMBL2854204 | 0.84 | DPP4 (0.74) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2709735 | 0.83 | DPP4 (0.98) | DPP4DPP8DPP9 | |
| SCHEMBL2854683 | 0.82 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| SCHEMBL2875271 | 0.82 | DPP4 (0.70) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930319-B1 | Proline derivatives and use thereof as drugs | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1308439-B1 | PROLINE DERIVATIVES AND USE THEREOF AS DRUGS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-1930319-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-06-11 | — | — | EP | disclosed |