SCHEMBL27110294

SCHEMBL27110294

Cc1ccccc1C1c2ccccc2C(C)C(OC(=O)c2ccoc2)C1OC(=O)c1ccoc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
PTPN6 P29350 1/20 0.44
PTPN11 Q06124 1/20 0.44
ABCB1 P08183 3/20 0.35
OPRK1 P41145 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTK2 Q05397 1/20 0.32
MAPT P10636 2/20 0.32
ITGAV P06756 1/20 0.31
ITGA2 P17301 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27053405 1.00 PTPN1 (0.44) PTPN1PTPN6PTPN11ABCB1OPRK1
SCHEMBL27105235 0.86 PTPN1 (0.56) PTPN1PTPN6PTPN11ABCB1OPRK1
SCHEMBL27053370 0.83 ABCB1 (0.45) ABCB1GAATSHRL3MBTL1MAPT
SCHEMBL24278847 0.83 ABCB1 (0.45) ABCB1GAATSHRL3MBTL1MAPT
SCHEMBL27110066 0.83 ABCB1 (0.45) ABCB1GAATSHRL3MBTL1MAPT
SCHEMBL27110249 0.81 KMT2A (0.36) ABCB1GAATSHRKDM4EHPGD
SCHEMBL27053394 0.81 KMT2A (0.36) ABCB1GAATSHRKDM4EHPGD
SCHEMBL27110291 0.81 POLB (0.42) ABCB1GAATSHRL3MBTL1MAPT
SCHEMBL27053402 0.81 POLB (0.42) ABCB1GAATSHRL3MBTL1MAPT
SCHEMBL27110201 0.80 BCHE (0.37) GAATSHRL3MBTL1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067763-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION METHOD, AND PROPYLENE POLYMER MITSUI CHEMICALS, INC. (JP) 2024-02-29 US disclosed