Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 19/20 | 0.70 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20813411 | 0.83 | ENPP1 (0.78) | ENPP1PDE1B | |
| SCHEMBL20814064 | 0.83 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL29857914 | 0.83 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL20814057 | 0.82 | ENPP1 (0.76) | ENPP1 | |
| SCHEMBL31502045 | 0.82 | ENPP1 (0.76) | ENPP1 | |
| SCHEMBL24015442 | 0.82 | ENPP1 (0.67) | ENPP1 | |
| SCHEMBL20814056 | 0.82 | ENPP1 (0.67) | ENPP1PDE1B | |
| SCHEMBL31502050 | 0.82 | ENPP1 (0.67) | ENPP1 | |
| SCHEMBL20813410 | 0.79 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL22299711 | 0.78 | ENPP1 (0.71) | ENPP1PDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327882-A2 | ENPP1 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-02-28 | — | — | EP | disclosed |