⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27125287 | 0.84 | — | — | |
| SCHEMBL27115718 | 0.78 | — | — | |
| SCHEMBL13652322 | 0.76 | — | — | |
| SCHEMBL11207115 | 0.69 | — | — | |
| SCHEMBL16659527 | 0.69 | — | — | |
| SCHEMBL26049716 | 0.69 | — | — | |
| SCHEMBL26049715 | 0.69 | — | — | |
| SCHEMBL22013053 | 0.68 | — | — | |
| SCHEMBL27115719 | 0.67 | TDP1 (0.32) | — | |
| SCHEMBL8178000 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044486-A1 | JAK2 INHIBITOR COMPOUNDS | AJAX THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |