Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.58 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 9/20 | 0.54 |
| ▸ | BCR | P11274 | 8/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | SRC | P12931 | 3/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116472 | 0.87 | CDK2 (0.57) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL27115951 | 0.87 | PIK3CG (0.62) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL27116136 | 0.86 | CLK1 (0.62) | CDK4CDK2ABL1BCRMAPK8 | |
| SCHEMBL27116468 | 0.85 | ABL1 (0.68) | PIK3CGCDK2ABL1BCRPDGFRB | |
| SCHEMBL7461678 | 0.85 | ABL1 (0.73) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4732256 | 0.84 | PLK1 (0.59) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL27116018 | 0.83 | ABL1 (0.55) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL14254272 | 0.82 | ABL1 (0.53) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL12801690 | 0.82 | PIK3CG (0.54) | CDC7CDK19PIK3CGPIK3CACDK4 | |
| SCHEMBL27116179 | 0.82 | PIK3CG (0.66) | CDC7CDK19PIK3CGPIK3CACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |