Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 15/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 15/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 15/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759601 | 1.00 | GRM5 (0.36) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20988952 | 0.96 | GRM5 (0.35) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL20988922 | 0.95 | GRM5 (0.34) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27118795 | 0.95 | GRM5 (0.37) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27117920 | 0.88 | GRM5 (0.37) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17381585 | 0.88 | GRM5 (0.36) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27118049 | 0.88 | GRM5 (0.35) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL30759592 | 0.88 | GRM5 (0.38) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27119377 | 0.88 | GRM5 (0.38) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB | |
| SCHEMBL27123287 | 0.86 | PIK3CD (0.39) | GRM5PIK3CDPIK3R2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044778-A2 | NOVEL MODULATORS OF FSHR AND USES THEREOF | CELMATIX INC. (US) | 2024-02-29 | — | — | WO | disclosed |