⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951568 | 0.78 | — | — | |
| SCHEMBL10152970 | 0.77 | MAPK1 (0.36) | — | |
| SCHEMBL30320251 | 0.76 | — | — | |
| SCHEMBL22992390 | 0.76 | — | — | |
| SCHEMBL27883669 | 0.74 | OR51E2 (0.31) | — | |
| SCHEMBL8744949 | 0.72 | — | — | |
| SCHEMBL24220954 | 0.71 | CYP2D6 (0.40) | — | |
| SCHEMBL25448178 | 0.71 | CYP2D6 (0.40) | — | |
| SCHEMBL14421430 | 0.70 | — | — | |
| SCHEMBL19557232 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044780-A1 | INTERLEUKIN-18 VARIANTS AND USES THEREOF | SUTRO BIOPHARMA, INC. (US) | 2024-02-29 | — | — | WO | disclosed |