Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506545 | 1.00 | WEE1 (0.59) | WEE1CYP3A4 | |
| SCHEMBL21373318 | 1.00 | WEE1 (0.59) | WEE1CYP3A4 | |
| SCHEMBL21373444 | 0.95 | WEE1 (0.59) | WEE1 | |
| SCHEMBL27124818 | 0.95 | WEE1 (0.59) | WEE1 | |
| SCHEMBL21373321 | 0.94 | WEE1 (0.57) | WEE1 | |
| SCHEMBL27129361 | 0.94 | WEE1 (0.57) | WEE1 | |
| SCHEMBL29506443 | 0.94 | WEE1 (0.57) | WEE1 | |
| SCHEMBL21373369 | 0.91 | WEE1 (0.60) | WEE1 | |
| SCHEMBL29506509 | 0.91 | WEE1 (0.60) | WEE1 | |
| SCHEMBL27130744 | 0.91 | WEE1 (0.60) | WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543242-B1 | 8,9-DIHYDROIMIDAZOLE[1,2-A]PYRIMIDO[5,4-E]PYRIMIDINE-5(6H)-KETONE COMPOUND | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2024-01-03 | — | — | EP | claimed |
| EP-3543242-B1 | 8,9-DIHYDROIMIDAZOLE[1,2-A]PYRIMIDO[5,4-E]PYRIMIDINE-5(6H)-KETONE COMPOUND | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2024-01-03 | — | — | EP | disclosed |