Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711688 | 0.96 | PIK3CA (0.62) | PIK3CAPIK3CD | |
| SCHEMBL2713669 | 0.93 | PIK3CA (0.62) | PIK3CAPIK3CD | |
| SCHEMBL2714957 | 0.88 | PIK3CA (0.51) | PIK3CAPIK3CD | |
| SCHEMBL2712869 | 0.86 | PIK3CA (0.55) | PIK3CAPIK3CD | |
| SCHEMBL2713564 | 0.84 | PIK3CD (0.54) | PIK3CAPIK3CD | |
| SCHEMBL2712813 | 0.84 | PIK3CA (0.50) | PIK3CAPIK3CD | |
| SCHEMBL2729435 | 0.83 | PIK3CA (0.60) | PIK3CAPIK3CD | |
| SCHEMBL2712822 | 0.83 | PIK3CA (0.59) | PIK3CAPIK3CD | |
| SCHEMBL2714017 | 0.82 | PIK3CA (0.53) | PIK3CAPIK3CD | |
| SCHEMBL2712503 | 0.80 | PIK3CD (0.53) | PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445886-B1 | 4-AMINOQUINOLINE DERIVATIVES AS PI3K INHIBITORS | AMGEN INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2445886-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | Amgen, Inc (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010151791-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2010-12-29 | — | — | WO | disclosed |