Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 13/20 | 0.63 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | CSF1R | P07333 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506471 | 1.00 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| SCHEMBL21373331 | 1.00 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| SCHEMBL30732422 | 1.00 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| SCHEMBL29506509 | 0.95 | WEE1 (0.60) | WEE1 | |
| SCHEMBL21373369 | 0.95 | WEE1 (0.60) | WEE1 | |
| SCHEMBL27130744 | 0.95 | WEE1 (0.60) | WEE1 | |
| Potrasertib SCHEMBL23246139 | 0.95 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| Potrasertib SCHEMBL21373352 | 0.95 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| Potrasertib SCHEMBL29859319 | 0.95 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC | |
| Potrasertib SCHEMBL29506543 | 0.95 | WEE1 (0.63) | WEE1EGFRCSF1RJAK2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543242-B1 | 8,9-DIHYDROIMIDAZOLE[1,2-A]PYRIMIDO[5,4-E]PYRIMIDINE-5(6H)-KETONE COMPOUND | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2024-01-03 | — | — | EP | disclosed |