Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783963 | 0.90 | MEN1 (0.68) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25063018 | 0.88 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6815864 | 0.87 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30142676 | 0.87 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30142859 | 0.87 | POLB (0.71) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24073684 | 0.87 | SMN1; SMN2 (0.74) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24073679 | 0.87 | KMT2A (0.64) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24073672 | 0.87 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24074064 | 0.87 | POLB (0.71) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10801453 | 0.87 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | KMT2A 1342/4885MEN1 3254/4885SMN1; SMN2 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.