SCHEMBL27140441

SCHEMBL27140441

Clc1cc2c(cn1)cc(Br)c1ocnc12

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31613256 1.00 CSNK2A1 (0.37) CSNK2A1
SCHEMBL31466959 0.73 CSNK2A1 (0.38) CSNK2A1
SCHEMBL31466963 0.71 NQO2 (0.43) CSNK2A1
SCHEMBL31467033 0.68 CSNK2A1 (0.38) CSNK2A1
SCHEMBL27139964 0.67 CSNK2A1 (0.33) CSNK2A1
SCHEMBL30780269 0.67 CSNK2A1 (0.33) CSNK2A1
SCHEMBL30780228 0.66 CSNK2A1 (0.37) CSNK2A1
SCHEMBL27139961 0.66 CSNK2A1 (0.37) CSNK2A1
SCHEMBL27139168 0.65 CSNK2A1 (0.39) CSNK2A1
SCHEMBL30780151 0.64 IKBKB (0.35) CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577546-A1 NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES Enliven Inc. (US) 2025-07-02 EP disclosed
WO-2024044713-A1 NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES ENLIVEN INC. (US) 2024-02-29 WO disclosed